A study in the Asian Pacific Journal of Cancer Prevention shows abortion increases the risk of breast cancer for women.
C. Yanhua of the First Peoples’ Hospital of Kunming in Yunnan province and his colleagues found the abortion-breast cancer association after comparing data from 263 cases of breast cancer and 457 controls without the disease. Their analysis covers the years 2009-2011.
The authors examined information on disease diagnosis, demographics, medical history, and reproductive characteristics of the patients involved and also looked at short menstrual cycle, old age at first live birth, never breastfeeding, history of oral contraceptive use, postmenopausal status and nulliparity to determine in abortion-breast cancer link exists.
They write that “multivariate model analysis revealed the significant independent positive associations with breast cancer of shorter menstrual cycle, older age at first live birth, never breastfeeding, history of oral contraception experience, increased number of abortion, menopause status, and nulliparities.”
“Number of abortion showed an increasing higher risk of breast cancer,” they added, while saying that women who had one live birth lowered their risk. “As far as women who had once a live birth, it showed decreased the risk of breast cancer compared to nulliparous.”
“This study showed an increased risk of breast cancer with times of abortion. The association between abortion and risk of breast cancer in a study in China showed that the risk factors of female breast cancer included abortion times more than two (Li et al., 2006),” they continued. “Another study found that risk was raised among women reporting at least one abortion, but no trend was seen with number of abortions (Heuch et al., 2008). In a meta-analysis study, pooled odds ratio for number of abortions greater than and equal three was statistically significant (95%CI:1.68-5.36) (Tao et al.,2011).”
“In conclusion, in this study the estrogen related risk factors of breast cancer included woman who had longer menstrual cycle, older age of first live birth, never breastfeeding, nulliparity, and number of abortions more than one. Therefore, it is recommended to women with these risk factors perform breast cancer screening tests earlier and regularly,” they said.
A study published in the Asian Pacific Journal of Cancer Prevention in February reported a very statistically significant increased risk of breast cancer for women with previous abortions as opposed to women who have never had one.
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The study, consisting of 1,351 women and led by researcher Ai-Ren Jiang, reported a statistically significant 1.52-fold elevation in risk for women with induced abortions and a “significant dose-response relationship between (the risk) for breast cancer and number of induced abortions,” meaning the risk climbed with a higher number of previous abortions.
For premenopausal women who have had abortions, the numbers were relatively small, and the observed 16% risk elevation was not statistically significant. However, for those with three or more abortions, the risk climbed to a statistically significant 1.55-fold elevation.